Henrietta Lacks' immortal cells are one of the most important and prolific tools in medicine, used in developing the polio vaccine, cloning and gene mapping.
But they were collected without permission, and her family never benefited from their use.
This week, Lacks' family finally reached a settlement with Massachusetts-based firm Thermo Fisher Scientific over their commercial use of the cells – dubbed HeLa cells after the first letters of Lacks' name.
But why is the case such a big deal? For those who are unaware, here's the tragic story behind the incredible legacy.
Henrietta Lacks was a mother of five who died of cervical cancer on 4 October 1951, when she was just 31 years old.
While Lacks, an African-American tobacco farmer, was being treated at the John Hopkins Hospital, two samples of her cervix were removed - a healthy part and a cancerous part - without her permission or knowledge.
These cells were passed onto Dr George Otto Gey, who discovered they could do something never seen before in humans cells - be kept alive and keep growing indefinitely.
Before this, cultured cells had only survived a few days in the lab.
Gey was able to isolate one specific cell and start the first ever immortal cell line, which he named HeLa.
They've been involved in thousands of medical breakthroughs and helped to develop the polio vaccine, cloning and gene mapping.
One researcher estimated that if you laid all the HeLa cells in existence end-to-end, they'd wrap around the planet at least three times.
In 2010, a tube of HeLa cells was selling for around US$260.
But unfortunately Henrietta's family were never compensated for her donation and most of them could't afford health insurance.
Journalist Rebecca Skloot wrote a best-selling book The Immortal Life of Henrietta Lacks on the subject in 2010.
After reading it, Dr Roland Pattillo of the Morehouse School of Medicine in the US donated a headstone for Lacks. For decades, her grave had been unmarked.
The headstone, which is shaped like a book, reads:
August 01, 1920 – October 04, 1951.
In loving memory of a phenomenal woman, wife and mother who touched the lives of many.
Here lies Henrietta Lacks (HeLa). Her immortal cells will continue to help mankind forever.
Eternal Love and Admiration, From Your Family
Thank you, Henrietta.
A version of this article was first published in April 2014.